Under the support and approval of the Shenzhen Municipal Bureau, BGI established Key Laboratories on symbiotic microorganisms and human health research and the transomics bioinformatics core technology.
Shenzhen Human commensal microorganisms and Health Research Key Laboratory based on the construction of BGI Shenzhen, established in November 2011 by Shenzhen Municipal Science and Technology Innovation Commission. The laboratory uses symbiotic microbes in the human body as the research object, relying on the advantages of a large platform and powerful sequencing analysis capabilities of BGI, focusing on the human body including the mouth, gastrointestinal tract, reproductive tract, skin and other parts of the microbial composition and microbial and human diseases, with research on the relationship between gut microbiota and health, fundamentally explain the pathogenesis of chronic metabolic diseases causes and try to make a "disease prevention, diagnosis, monitoring and improvement"model. The main research directions include: human gut microbes and dietary research, gut microbes and disease research, and metabolism of gut microbes and host, the host genotype studies.
Shenzhen transomics bioinformatics core technology Key Laboratory was established in 2011 under the Shenzhen Municipal Bureau of Commission approval. The core research direction of this laboratory is to develop multi-core research direction genomics bioinformatics core integration technology, to take a series of important life sciences problem for systematic study, mainly including: (1) Genomics Research: the main R & D sequence assembly and alignment methods, different genome genetic variation detection methods, different genomic level of "omics" analysis techniques; (2) Genomics association studies: development of appropriate genomics, genomics and characters and other aspects related research strategy; complex disease genome-wide association analysis, macro genome association analysis methods; (3) Genomics system integration research: research and development, including through group learning system integrated research strategy, biological systems modeling and recognition. Research directions including: developing more integrated genomics bioinformatics core technologies, from a system perspective at all levels of the life process, a series of important issues for life science research system.