RNA

Transcriptomics is the study of the transcriptome using high-throughput methods to reveal the presence, quantity and structure of coding RNA and non-coding RNA in a biological sample under specific conditions. Compared to hybridization-based RNA quantification methods such as microarray analysis, sequencing-based transcriptome detection can quantify gene expression with low background, high accuracy and high levels of reproducibility within a large dynamic range. In addition, it can detect mutations, splice variants and fusion genes. BGI offers a full range of transcriptome sequencing services, and professional and customized bioinformatics services.

Transcriptome sequencing
RNA-Seq
Small RNA sequencing
Long non-coding RNA sequencing
circRNA sequencing
Full length transcriptome sequencing

Epigenomics

Epigenomics refers to the study of epigenetics modification at the genomic level. It studies the modification of non-DNA sequence changes in the context of "omics," which has led to an increase in genomic research and a new point of view: For the genome, not only the DNA sequence contains genetic information, but its modification can also record genetic information.

BGI has devoted itself to the study of epigenomics, using its powerful sequencing platform and many years of successful experience to help researchers accelerate the discovery, increase understanding of the mechanism of the epigenetic system, and have a more comprehensive understanding of gene function. In recent years, BGI has published nearly 50 articles in epigenomics, including articles with high Impact Factor, such as Yanhuang methylation sequencing and Bombyx Mori methylation sequencing. BGI provides epigenomics sequencing including genome-wide bisulfite sequencing, ChIP-seq and customized products such as target region methylation sequencing, ATAC-Seq,OxBS.

Whole genome bisulfite sequencing
ChIP-Seq

Proteomics

The word proteome is a combination of protein and genome and was coined by Mark Wilkins in 1994 to describe the protein complement of a genome. Proteomics can be defined as “a large-scale study of protein properties, e.g., expression level, posttranscriptional modification and protein interaction, in order to obtain a global view of disease processes or cellular processes at the protein level.” Mass spectrometry (MS)–based proteomics has matured into an attractive technology for the global analysis of protein composition, modifications, and dynamics in cell biology, which is usually carried out by tandem MS (MS/MS or MS2) and coupled to high performance liquid-chromatography (LC). BGI offers a series of proteomics and bioinformatics analysis solutions based on our leading-edge MS platform and our demonstrated expertise.

DIA Quantitative Proteomics
iTRAQ Quantitative Proteomics
Targeted Protein Quantitation
Proteome Profiling
PTM Profiling

Metabonomics

Metabolomics is an emerging and rapidly evolving “omics-level” research technology tool, which involves quantitative and qualitative metabolite assessments in biological systems. Combining high-throughput analytical chemistry and multivariate data analysis, metabolomics offers a brand new perspective for studies on metabolic mechanisms. It offers tremendous promise for diverse applications in various fields such as medical, nutrition, environmental, and agricultural sciences. BGI provides scalable, customizable metabolomics services across the research continuum from discovery to targeted analysis.

Untargeted Metabolomics
Lipidomics
Targeted Metabolomics

Tech Solutions

RNA

Epigenomics

Proteomics

Metabonomics