Formalin-fixed, paraffin-embedded (FFPE) tissues represent the predominant sample conservation method in clinical practice, yet degraded and crosslinked RNA has long limited whole-transcriptome analysis and spatial context. On August 28, in Cell, researchers at BGI-Research and collaborating c...
Learn details
In a remarkable demonstration of scientific process spanning the entire tree of life, BGI-Research and collaborating institutes report three groundbreaking studies that showcase how cutting-edge CycloneSEQ nanopore sequencing technology has successfully decoded complete genomes from a bearded dragon...
Learn details
On August 21, the State Key Laboratory of Genome and Multi-omics Technologies, led by BGI-Research, collaborated with multiple institutions to unveil a groundbreaking single-cell omics technology named Stereo-cell in Science. This technology represents a transformative advancement in cellular analys...
Learn details
BGI-Research recently announced SpaSEG, a new unsupervised deep-learning framework designed to significantly improve spatially resolved transcriptomics (SRT) multi-task analysis. This powerful method reveals the precise distribution of gene expression across intact tissues.Described in a paper ...
Unlocking the mysteries of the brain - our most complex and powerful organ - remains one of science’s greatest challenges. Understanding how billions of diverse neurons form networks that enable perception, memory, and behavior is key to tackling brain diseases and advancing human knowledge. BG...
The brain comprises a vast array of neuron types, interconnected in complex networks that underpin functions such as sensory perception, learning, memory, and motor control. Therefore, understanding the brain is essential for deciphering these functions and addressing related diseases. At the fore...
For the estimated 416 million people worldwide on the Alzheimer's disease continuum, including 316 million in preclinical stages, current treatment options remain frustratingly limited. While decades of research have focused on clearing amyloid beta protein deposits from the brain, this approach...
For decades, liquid biopsy tests have analyzed the size and positioning of double-stranded cell free DNA (cfDNA) fragments in blood, but they ignore the single-stranded fragments that escape conventional detection. In a study published in Clinical Chemistry, scientists at BGI-Research report that cf...
For more than a century, scientists have marveled at the striking disparities in regenerative ability across mammalian species. A rabbit can mend a hole punched clean through its outer ear in about a month, followed by the complete regeneration of internal structures (including cartilage, blood...